use strict;
my $str = '
Wells managment has shared a mandetory file with you
Wells MailBox Managment Center
wells mailbox management center
';
my $regex = qr/((?:w|W)ells (?:M|m)ail(?:B|b)ox (?:Managment|Management|managment|management) (?:C|c)enter)/imp;
my $subst = '';
my $result = $str =~ s/$regex/$subst/rg;
print "The result of the substitution is' $result\n";
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Perl, please visit: http://perldoc.perl.org/perlre.html