use strict;
my $str = 'www.1edisource.com/ediresources/editradingpartnerupdates.aspx?urlid=123
www.1edisource.com/ediresources/editradingpartnerupdates.aspx?urlid=123&gclid=jjj
www.1edisource.com/ediresources/editradingpartnerupdates.aspx
www.1edisource.com/ediresources/editradingpartnerupdates.aspx?gclid=jjj';
my $regex = qr/(?i)(EDIResources\/EDITradingPartnerUpdates\.aspx)(.*)/ip;
my $subst = 'resources/edi-tips$2';
my $result = $str =~ s/$regex/$subst/rg;
print "The result of the substitution is' $result\n";
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Perl, please visit: http://perldoc.perl.org/perlre.html