const regex = new RegExp('(#+)', 'mg')
const str = `### Start of program
number = 0 ## Initialize the variable
number += 1 # Increment the variable`;
const subst = `\/\/`;
// The substituted value will be contained in the result variable
const result = str.replace(regex, subst);
console.log('Substitution result: ', result);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for JavaScript, please visit: https://developer.mozilla.org/en/docs/Web/JavaScript/Guide/Regular_Expressions