use strict;
my $str = '1
10
100
1000
10000
100000
1000000
10000000
100000000
1000000000
10000000000
100000000000
';
my $regex = qr/(\d)(?=(\d{3})+\b)/p;
my $subst = '$1,';
my $result = $str =~ s/$regex/$subst/rg;
print "The result of the substitution is' $result\n";
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Perl, please visit: http://perldoc.perl.org/perlre.html