$re = '/((?:[0-9]{1,3},(?:[0-9]{3},)*[0-9]{3}|[0-9]+)(?:.[0-9][0-9])?)\s*(?:ש\"ח|₪|nis|NIS|שקל)(?:\W|$)/';
$str = '10,100,000nis
100.00 ש"ח
sfdsf sd34 sdf 3.00 nis
5,000 שקל';
preg_match_all($re, $str, $matches, PREG_SET_ORDER, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php