$re = '/(?:(?<=\.(?:com|cn)(\:\d+(?!\d)))|(?<=\.(?:com|cn)(?!:\d+|\.)))(?!\/)/';
$str = 'https://live-rv.duizhuang.com:123aaa/bb
https://live-rv.duizhuang.com:123/aaa/bb
https://live-rv.duizhuang.com/aaa/bb
https://live-rv.duizhuang.cn2/aaa/bb
https://img.dz8.cn/2/aaa/bb.png!/1/1
';
$subst = "/";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php