$re = '/(\d{1})[-](\d{3})[-](\d{3})[-](\d{4})/m';
$str = '2124567890
212-456-7890
(212)456-7890
(212)-456-7890
212.456.7890
212 456 7890
+12124567890
+12124567890
+1 212.456.7890
+212-456-7890
1-212-456-7890
1-21-345-7890
';
$subst = "";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php