$re = '/<VirtualHost[*:0-9\s]+>([\S\s]+?)<\/VirtualHost>/';
$str = '...
# First VHost...
<VirtualHost *:80 *:8082>
# Any number of configs
# and set up options for
# Apache
</VirtualHost>
# Second VHost...
<VirtualHost *:80 *:8082>
# Any number of configs
# and set up options for
# Apache
</VirtualHost>
# Third VHost...
<VirtualHost *:80 *:8082>
# Any number of configs
# and set up options for
# Apache
</VirtualHost>
....';
preg_match_all($re, $str, $matches, PREG_SET_ORDER, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php