$re = '/^https:\/\/twitter.com\/(?!messages|notifications|settings)[a-zA-Z0-9_]{4,15}($|\/)/m';
$str = 'https://twitter.com/settings/account
https://twitter.com/messages
https://twitter.com/notifications
https://twitter.com/donate4_fun
https://twitter.com/donate4_fun/zxcqwe
https://twitter.com/nbryskin
https://twitter.com/jack
https://twitter.com/i/asd';
preg_match_all($re, $str, $matches, PREG_SET_ORDER, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php