$re = '/P(ost)?[\.\s]*(O|0)(ff(ice)?)?[\.\s]+B(o|0)x/mi';
$str = 'PO Box
P.O. Box
PO. Box
po box
P.o box
PoBox
p.o. Box
post office box 716
Post O. box
Post off box
p office box
p off BOX
p0 box
p0ffice box k';
preg_match_all($re, $str, $matches, PREG_SET_ORDER, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php