$re = '~^(?:[0-9]{1,3}\. ?)?(?:<media(?::[0-9]+)? ?/?><br ?/?>)*(.*)$~m';
$str = 'What does the speaker suggest?
91. What does the speaker suggest?
96. <media:12 /><br />Why is the speaker going to Reynold’s Café?
96. <media:12 /><br /><media:13 /><br />Why is the speaker going to Reynold’s Café?';
$subst = "$1";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php