use strict;
my $str = 'What does the speaker suggest?
91. What does the speaker suggest?
96. <media:12 /><br />Why is the speaker going to Reynold’s Café?
96. <media:12 /><br /><media:13 /><br />Why is the speaker going to Reynold’s Café?';
my $regex = qr~^(?:[0-9]{1,3}\. ?)?(?:<media(?::[0-9]+)? ?/?><br ?/?>)*(.*)$~mp;
my $subst = '$1';
my $result = $str =~ s~$regex~$subst~rg;
print "The result of the substitution is' $result\n";
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Perl, please visit: http://perldoc.perl.org/perlre.html