re = /\G((?:.\D)*.)\d/
str = 'a1b2cde3~g45hi6
Match any char with a non digit ( This is to ensure that the /G carries on to the next pair)
store any char in \\1
Match any digit'
subst = '$1*'
result = str.gsub(re, subst)
# Print the result of the substitution
puts result
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Ruby, please visit: http://ruby-doc.org/core-2.2.0/Regexp.html