re = /^([A-Z]|[a-z]|\s)+(,\s*(Jr\.|Sr\.|[IV]*))?$/m
str = ' John Smith, Jr.
Winn Thomas
Mary 3llen Jones
Clyde Franklin, III
wallace firt, the
wimbobimbo ff , VIVIVVVVIIIVIIVVI
s f asdf s dfFASFSf dsf saf sFD s faS fdy t sg , Sr.'
subst = 'Ye Tar Oo Yetaroo3 Uyetar Goffery '
result = str.gsub(re, subst)
# Print the result of the substitution
puts result
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Ruby, please visit: http://ruby-doc.org/core-2.2.0/Regexp.html