$re = '/\s*([a-zA-Z])(?(?=\S*?[qwrtpsdfghjklzxcvbnmQWRTPSDFGHJKLZXCVBNM]\S)(?:\S*?)([qwrtpsdfghjklzxcvbnmQWRTPSDFGHJKLZXCVBNM])|([eyuioaEYUIOA]))?[a-zA-Z]*?([a-zA-Z])?[-\?\.,\s+]/';
$str = 'I am. Now this is not the end. It is not even the beginning of the end. But it is, perhaps, the end of the beginning ## philosophy.';
preg_match_all($re, $str, $matches, PREG_SET_ORDER, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php