$re = '/(?i)(\b|[¡¿])(?<uno>[^\s]+\s[^,]+),\s(\k<uno>)([?!]|\b)/m';
$str = '- Dios mÃo, ¡está aquÃ, está aquÃ!
- ¿Qué paso, qué paso?
- Me rehúso, me rehúso.';
$subst = "$1$2$4";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php