$re = '/\d{3}([ .-])?\d{3}([ .-])?\d{4}|\(\d{3}\)([ ])?\d{3}([.-])?\d{4}|\(\d{3}\)([ ])?\d{3}([ ])?\d{4}|\(\d{3}\)([.-])?\d{3}([.-])?\d{4}|\d{3}([ ])?\d{3}([ .-])?\d{4}/m';
$str = '(123).234.4567
(123)-234-4567
(617) 495-1797
(617) 495 1797
(617) 4951797
6174951797
617 4951797
123.234.4567
123-456-4567
123.123-1234
123.123-1234
123 123-1234
123 123 1234';
$subst = "";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php