const regex = /(comment_approved\s=\s\'(?:1|0)\')|\(\s(comment_approved\s=\s'0'\sOR\scomment_approved\s=\s'1')\s\)/;
// Alternative syntax using RegExp constructor
// const regex = new RegExp('(comment_approved\\s=\\s\\\'(?:1|0)\\\')|\\(\\s(comment_approved\\s=\\s\'0\'\\sOR\\scomment_approved\\s=\\s\'1\')\\s\\)', '')
const str = `( comment_approved = '0' OR comment_approved = '1' ) AND ( (CAST(wp_72423799_commentmeta.meta_value AS SIGNED) >= '1409095998') ) AND (wp_72423799_commentmeta.meta_key = 'o2_comment_gmt_modified' )
`;
const subst = `( $1$2 OR comment_approved = \'trash\' )`;
// The substituted value will be contained in the result variable
const result = str.replace(regex, subst);
console.log('Substitution result: ', result);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for JavaScript, please visit: https://developer.mozilla.org/en/docs/Web/JavaScript/Guide/Regular_Expressions