import Foundation
let pattern = #"(me)(?!([^<]+)?>)"#
let regex = try! NSRegularExpression(pattern: pattern, options: .caseInsensitive)
let testString = #"I have ever been prone to seek adventure and to investigate and experiment where <span class='me'>wiser men</span> would have left well enough alone."#
let stringRange = NSRange(location: 0, length: testString.utf16.count)
let substitutionString = #"<span class='highlight'>$1</span>"#
let result = regex.stringByReplacingMatches(in: testString, range: stringRange, withTemplate: substitutionString)
print(result)
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Swift 5.2, please visit: https://developer.apple.com/documentation/foundation/nsregularexpression