$re = '/((\d+)(?=\/))(?!.*\1)/m';
$str = '/designer-dev/22/Staging/Datawatch/English/hotfix/22.1.4/InternalBuild/1.2.3.44/AltairPanopticonVisualizationServerWAR_22-1-4.zip';
preg_match_all($re, $str, $matches, PREG_SET_ORDER, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php