$re = '/^\/([ac])\/(\d{1,4})\/(\d{1,4})\/([a-zA-Z\d\._-]+)\/(.*)/x';
$str = '/a/94/403/webolizer/1461075495.84270.webmail5581.mynet.com%3A1228350129winmail.dat';
$subst = "";
$result = preg_replace($re, $subst, $str, 1);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php