const regex = /^.+?\K(\,)/gm;
// Alternative syntax using RegExp constructor
// const regex = new RegExp('^.+?\\K(\\,)', 'gm')
const str = `2009 CITROEN BERLINGO FIRST HDI 1.6 DIESEL, Cherry Red, PAS, Rear sliding doors, Locally owned .......................................NOW SOLD
2012 FORD GRAND C-MAX ZETEC 1.6 PETROL, 47,574 Miles, 1 Owner from New, 7 Seater...................................WAS £6,995 NOW £6,495!
2007 JEEP CHEROKEE SRI CD LIMITED EDITION, Sat Nav/ Radio, Leather Heated Seats ......................................................................SOLD!
`;
const subst = `\t`;
// The substituted value will be contained in the result variable
const result = str.replace(regex, subst);
console.log('Substitution result: ', result);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for JavaScript, please visit: https://developer.mozilla.org/en/docs/Web/JavaScript/Guide/Regular_Expressions