$re = '/[^A-Za-z 0-9 \.,\?""!@#\$%\^&\*\(\)-_=\+;:<>\/\\\\\|\}\{\[\]`~|\xE0-\xE6|\xC0-\xC6|\xE8-\xEB|\xC8-\xCB|\xEC-\xEF|\xCC-\xCF|\xF2-\xF6|\xD2-\xD6|\xF9-\xFC|\xD9-\xDC|\xE7|\xC7|\xF1|\xD1]*/';
$str = 'aÇÃO
ANÃO
único
Único
íma
irmão';
preg_match_all($re, $str, $matches, PREG_SET_ORDER, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php