$re = '/\s(?=[\s":{}])/';
$str = '{
"failure": {
"type": "Blah",
"message": "Unrecognised Message: \\"Good job!\\" Sir"
}
}';
$subst = "";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php